The railway authorities are requiring passengers to scan health codes and have their temperatures checked when entering the stations, and the wearing of masks is mandatory to reduce risk of infection.
At 7:25, the flight MU2527 bound for Sanya, Hainan province, took off from Wuhan Tianhe International Airport, signaling the resumption of air traffic in Wuhan.
The airport is expected to see more than 200 inbound and outbound domestic flights on the day, according to the airport authority.
Big data from Wuhan traffic police forecasted expressways would see a peak of outbound vehicles on Wednesday.
On Jan 23, Wuhan declared unprecedented traffic restrictions, including suspending the city's public transport and all outbound flights and trains, in an attempt to contain the epidemic.